Are there any specific comic book series or titles that focus primarily on Betty and Veronica's adventures without Archie as the central figure?

Yes, Betty and Veronica have starred in numerous spin-off series and titles over the years. Examples include 'Betty and Veronica,' 'Betty and Veronica Spectacular,' 'Betty and Veronica Double Digest,' and 'Betty & Veronica Jumbo Comics Digest,' which often feature stories where Archie is a secondary character or absent entirely. More recently, the 'New Riverdale' reboot included its own 'Betty & Veronica' series, offering modern takes on their friendship and individual adventures.